In a notable convergence of traditional industries and the burgeoning digital asset space, 180 Life Sciences, a biotechnology firm, has announced a significant strategic pivot. Rebranded as ETHZilla, the company is reorienting its core business to establish a substantial Ethereum treasury, marking an ambitious foray into the cryptocurrency market supported by plans to raise over half a billion dollars.
- 180 Life Sciences has rebranded as ETHZilla.
- The company is shifting its core focus to building an Ethereum treasury.
- It aims to raise $425 million through a PIPE for direct Ethereum acquisition.
- An additional $150 million is targeted via debt securities post-PIPE.
- ETHZilla plans a “differentiated blockchain-based yield generation program” with Electric Capital, targeting 3%-10% returns.
- The firm aspires to become a dominant global owner of Ethereum through reinvestment of generated yield.
Strategic Financials and Yield Generation
This strategic transformation is predicated on securing $425 million through a Private Investment in Public Equity (PIPE) transaction, priced at $2.65 per share. These funds are explicitly earmarked for the exclusive acquisition of Ethereum (ETH). Furthermore, an additional $150 million is targeted via debt securities, to be raised post-PIPE closing, aimed at further expanding its digital asset holdings. McAndrew Rudisill, the newly appointed Chairman, underscored Ethereum’s robust capabilities for asset management and income generation, envisioning the establishment of a “true yield curve” to ensure sustained revenue streams.
To optimize its returns and digital asset growth, ETHZilla intends to collaborate with external asset manager Electric Capital. This partnership will focus on developing a “differentiated blockchain-based yield generation program,” designed to transcend the returns typically associated with traditional Ethereum staking. The program targets yield generation between 3% and 10%, contingent on prevailing market conditions. Rudisill further characterized ETHZilla as an “operational business with high margins and significant fixed operating leverage,” strategically structured to generate Earnings Before Interest, Taxes, Depreciation, and Amortization (EBITDA) and positive free cash flow, which will be reinvested into acquiring more ETH. This model, he suggested, positions ETHZilla as a distinctive player within the evolving landscape of corporate treasury solutions.
Market Context and Vision
ETHZilla’s strategic pivot aligns with a burgeoning trend among public companies establishing substantial Ethereum treasuries. This movement is exemplified by entities such as SharpLink Gaming, which reportedly holds a notable 438,017 ETH. The chosen name, “ETHZilla,” itself encapsulates the company’s expansive vision, underscoring its ambition to accumulate significant Ethereum holdings and systematically reinvest yield-generated cash flow, with the ultimate goal of becoming a dominant global owner of the asset. This strategic maneuver is further contextualized by broader market dynamics, including substantial “whale” accumulation of Ethereum; analyses by firms like Lookonchain indicate that large holders have acquired over $2.4 billion in ETH since July, reinforcing the asset’s growing institutional appeal.

Blockchain developer and writer, Daniel combines hands-on coding experience with accessible storytelling. He holds multiple blockchain certifications and authors technical explainers, protocol deep-dives, and developer tutorials to help readers navigate the intersection of code and finance.